Thoracic Paravertebral Blockade Reduces Chronic Postsurgical Pain in Breast Cancer Patients: A Randomized Controlled Trial.

ABSTRACT:

Objective

To evaluate the effect of multilevel single-shot thoracic paravertebral blockade (PVB) on the occurrence of chronic postsurgical pain (CPSP) in patients undergoing breast cancer surgery.

Design

A randomized controlled trial with two parallel groups.

Setting

A tertiary hospital.

Methods

Patients scheduled for breast cancer surgery were randomized to receive either ultrasound-guided multilevel single-shot PVB from T2 to T5 (the PVB group) or nothing (the control group). Surgery was then performed under general anesthesia. Patients were followed up for 12 months after surgery. The primary end point was incidence of CPSP at six months after surgery.

Results

A total of 218 patients were enrolled and randomized; of these, 208 and 204 completed six- a

SUBMITTER: Lin ZM 

PROVIDER: S-EPMC7770235 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature