Global, Regional, and National Burden of Chronic Myeloid Leukemia, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017.

ABSTRACT:

Background

With the advent of tyrosine kinase inhibitors (TKIs), the prognosis of chronic myeloid leukemia (CML) seems to have dramatically improved over the last two decades. Accurate information of the global burden of CML is critical for direct health policy and healthcare resource allocation in the era of high-cost TKI therapy.

Objective

This study aimed to evaluate the health burden of CML at global, regional, and national levels from 1990 to 2017.

Methods

We collected data of CML between 1990 and 2017 from the Global Burden of Disease (GBD) study 2017 including, annual incidence, disease-related mortality, and disability-adjusted life-years (DALY), and the corresponding age-standardized rates (ASRs). To summarize the results, countries were categorized by sociod

SUBMITTER: Lin Q 

PROVIDER: S-EPMC7770240 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature