Pathologic Predictors of Survival During Lymph Node Dissection for Metastatic Renal-Cell Carcinoma: Results From a Multicenter Collaboration.

ABSTRACT:

Purpose

To determine the therapeutic value of lymph node dissection (LND) during cytoreductive nephrectomy (CN) and assess predictors of cancer-specific survival (CSS) in metastatic renal-cell carcinoma.

Patients and methods

We identified 293 consecutive patients treated with CN at 4 academic institutions from March 2000 to May 2015. LND was performed in 187 patients (63.8%). CSS was estimated by the Kaplan-Meier method for the entire cohort and for a propensity score-matched cohort. Cox proportional hazards regression was used to evaluate CSS in a multivariate model and in an inverse probability weighting-adjusted model for patients who underwent dissection.

Results

Median follow-up was 12.6 months (interquartile range, 4.47, 30.3), and median survival was 15.9 month

SUBMITTER: Chipollini J 

PROVIDER: S-EPMC7771342 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature