Diagnosis and management of immune-related adverse effects of immune checkpoint therapy in the emergency department.

ABSTRACT: Rapid advances in cancer immunotherapy using immune checkpoint inhibitors have led to significantly improved survival. Rapid identification of the toxicity syndromes associated with these therapeutic agents is very important for emergency physicians because the population of patients diagnosed with cancer is increasing and cancer therapies including immune checkpoint inhibitors have become the first-line treatment for more and more types of cancer. The emergency medicine literature lags behind rapid advances in oncology, and oncology guidelines for rapid recognition and management of these emerging toxicity syndromes are not familiar to emergency physicians. In this review article, we discuss the clinical presentation and management of immune-related adverse effects during the critical fir

SUBMITTER: Yeung SJ 

PROVIDER: S-EPMC7771833 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature