Differences in the Performance of Allyl Based Palladium Precatalysts for Suzuki-Miyaura Reactions.

ABSTRACT: Palladium(II) precatalysts are used extensively to facilitate cross-coupling reactions because they are bench stable and give high activity. As a result, precatalysts such as Buchwald's palladacycles, Organ's PEPPSI species, Nolan's allyl-based complexes, and Yale's 1-tert-butylindenyl containing complexes, are all commercially available. Comparing the performance of the different classes of precatalysts is challenging because they are typically used under different conditions, in part because they are reduced to the active species via different pathways. However, within a particular class of precatalyst, it is easier to compare performance because they activate via similar pathways and are used under the same conditions. Here, we evaluate the activity of different allyl-based preca

SUBMITTER: Espinosa MR 

PROVIDER: S-EPMC7771882 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature