Acute kidney injury in renal transplant recipients undergoing cardiac surgery.

ABSTRACT:

Background

Acute kidney injury (AKI) is a key risk factor for chronic kidney disease in the general population, but has not been investigated in detail among renal transplant recipients (RTRs). We investigated the incidence, severity and risk factors for AKI following cardiac surgery among RTRs compared with non-RTRs with otherwise similar clinical characteristics.

Methods

We conducted a retrospective cohort study of RTRs (n = 83) and non-RTRs (n = 83) who underwent cardiac surgery at two major academic medical centers. Non-RTRs were matched 1:1 to RTRs by age, preoperative (preop) estimated glomerular filtration rate and type of cardiac surgery. We defined AKI according to Kidney Disease: Improving Global Outcomes criteria.

Results

RTRs had a higher rate of AKI follo

SUBMITTER: Hundemer GL 

PROVIDER: S-EPMC7771983 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature