Determinants of dengue virus dispersal in the Americas.

ABSTRACT: Dengue viruses (DENVs) are classified into four serotypes, each of which contains multiple genotypes. DENV genotypes introduced into the Americas over the past five decades have exhibited different rates and patterns of spatial dispersal. In order to understand factors underlying these patterns, we utilized a statistical framework that allows for the integration of ecological, socioeconomic, and air transport mobility data as predictors of viral diffusion while inferring the phylogeographic history. Predictors describing spatial diffusion based on several covariates were compared using a generalized linear model approach, where the support for each scenario and its contribution is estimated simultaneously from the data set. Although different predictors were identified for different seroty

SUBMITTER: Allicock OM 

PROVIDER: S-EPMC7772473 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature