The functional connectome predicts feeling of stress on regular days and during the COVID-19 pandemic.

ABSTRACT: Although many studies have explored the neural mechanism of the feeling of stress, to date, no effort has been made to establish a model capable of predicting the feeling of stress at the individual level using the resting-state functional connectome. Although individuals may be confronted with multidimensional stressors during the coronavirus disease 2019 (COVID-19) pandemic, their appraisal of the impact and severity of these events might vary. In this study, connectome-based predictive modeling (CPM) with leave-one-out cross-validation was conducted to predict individual perceived stress (PS) from whole-brain functional connectivity data from 817 participants. The results showed that the feeling of stress could be predicted by the interaction between the default model network and salien

SUBMITTER: Liu P 

PROVIDER: S-EPMC7772572 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature