Ex vivo Comprehensive Multiphase NMR of whole organisms: A complementary tool to in vivo NMR.

ABSTRACT: Nuclear Magnetic Resonance (NMR) spectroscopy is a non-invasive analytical technique which allows for the study of intact samples. Comprehensive Multiphase NMR (CMP-NMR) combines techniques and hardware from solution state and solid state NMR to allow for the holistic analysis of all phases (i.e. solutions, gels and solids) in unaltered samples. This study is the first to apply CMP-NMR to deceased, intact organisms and uses ¹³C enriched Daphnia magna (water fleas) as an example. D. magna are commonly used model organisms for environmental toxicology studies. As primary consumers, they are responsible for the transfer of nutrients across trophic levels, and a decline in their population can potentially impact the entire freshwater aquatic ecosystem. Though in viv

SUBMITTER: Ghosh Biswas R 

PROVIDER: S-EPMC7772632 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature