Quantitative proteomic analysis of chicken serum reveals key proteins affecting follicle development during reproductive phase transitions.

ABSTRACT: Avian reproductive behavior is regulated through the neuroendocrine system. The transition from laying to brooding is strictly controlled by the hypothalamus-pituitary-gonadal (HPG) axis. Cross talk on the HPG axis relies on the circulatory system, where the dynamics of serum proteins can be observed during different reproductive phases. Some canonical hormones, such as prolactin and luteinizing hormone, play important roles in the transition through reproductive phases. However, little is known at the whole-proteome level. To discover novel serum proteins, we employed isobaric tags for relative and absolute quantification to assay the serum proteome during different reproductive phases in chicken. We identified a total of 1,235 proteins from chicken serum; 239 of these proteins showed dif

SUBMITTER: Shen X 

PROVIDER: S-EPMC7772657 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature