Standardised computed tomographic assessment of left atrial morphology and tissue thickness in humans.

ABSTRACT:

Aims

Left atrial (LA) remodelling is a common feature of many cardiovascular pathologies and is a sensitive marker of adverse cardiovascular outcomes. The aim of this study was to establish normal ranges for LA parameters derived from coronary computed tomographic angiography (CCTA) imaging using a standardised image processing pipeline to establish normal ranges in a previously described cohort.

Methods

CCTA imaging from 193 subjects recruited to the Budapest GLOBAL twin study was analysed. Indexed LA cavity volume (LACV_i), LA surface area (LASA_i), wall thickness and LA tissue volume (LATV_i) were calculated. Wall thickness maps were combined into an atlas. Indexed LA parameters were compared with clinical variables to identify early markers

SUBMITTER: Whitaker J 

PROVIDER: S-EPMC7772783 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature