Clinical Trials in Metastatic Uveal Melanoma: Current Status.

ABSTRACT:

Background

Uveal melanoma is a rare subtype of melanoma. Prognosis and survival rates for patients with metastatic uveal melanoma remain poor. No current FDA-approved standard of care therapy is available for patients with metastatic uveal melanoma. Thus, clinical trials are essential for the development of new therapies and to provide patients hope for improved survival and outcomes.

Summary

In this article, we review clinical trials identified on the database https://clinicaltrials.gov that are open and enrolling patients with metastatic uveal melanoma as of November 26, 2019. This search produced 17 active trials involving liver-directed therapy, CNS-directed therapy, and systemic therapy with immunotherapy, targeted therapy, or oncolytic virus therapy. Here, we discuss l

SUBMITTER: Sussman TA 

PROVIDER: S-EPMC7772871 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature