Correlative Magnetic Resonance Imaging and Histopathology in Small Ruminant Listeria Rhombencephalitis.

ABSTRACT: Background: Listeria rhombencephalitis, infection of the brainstem with Listeria monocytogenes, occurs mainly in humans and farmed ruminants and is associated with high fatality rates. Small ruminants (goats and sheep) are a large animal model due to neuropathological similarities. The purpose of this study was to define magnetic resonance imaging (MRI) features of listeria rhombencephalitis in naturally infected small ruminants and correlate them with histopathology. Secondly, the purpose of this study was to compare the results with MRI findings reported in humans. Methods: Twenty small ruminants (13 sheep and 7 goats) with listeria rhombencephalitis were prospectively enrolled and underwent in vivo MRI of the brain, including T2-weighted, fluid attenuation in

SUBMITTER: Precht C 

PROVIDER: S-EPMC7773005 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature