PhyloGenes: An online phylogenetics and functional genomics resource for plant gene function inference.

ABSTRACT: We aim to enable the accurate and efficient transfer of knowledge about gene function gained from Arabidopsis thaliana and other model organisms to other plant species. This knowledge transfer is frequently challenging in plants due to duplications of individual genes and whole genomes in plant lineages. Such duplications result in complex evolutionary relationships between related genes, which may have similar sequences but highly divergent functions. In such cases, functional inference requires more than a simple sequence similarity calculation. We have developed an online resource, PhyloGenes (phylogenes.org), that displays precomputed phylogenetic trees for plant gene families along with experimentally validated function information for individual genes within the families. A to

SUBMITTER: Zhang P 

PROVIDER: S-EPMC7773024 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature