Pilot study of fractional CO₂ laser therapy for genitourinary syndrome of menopause in gynecologic cancer survivors.

ABSTRACT:

Purpose

The objectives of this study were to evaluate the feasibility and efficacy of fractional CO₂ laser therapy in gynecologic cancer survivors.

Methods

This was a pilot, multi-institutional randomized sham-controlled trial of women with gynecologic cancers with dyspareunia and/or vaginal dryness. Participants were randomized to fractional CO₂ laser treatment or sham laser treatment. The primary aim was to estimate the proportion of patients who had improvement in symptoms based on the Vaginal Assessment Scale (VAS). Secondary aims included changes in sexual function assessed using the Female Sexual Functioning Index (FSFI) and urinary symptoms assessed using the the Urinary Distress Inventory (UDI-6).

Results

Eighteen women participated in th

SUBMITTER: Quick AM 

PROVIDER: S-EPMC7773136 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature