Associations Between Fetal Growth Trajectories and the Development of Myopia by 20 Years of Age.

ABSTRACT:

Purpose

To evaluate the contribution of genetic and early life environmental factors, as reflected by fetal anthropometric growth trajectories, toward the development of myopia during childhood and adolescence.

Methods

This analysis included 498 singleton Caucasian participants from the Raine Study, a pregnancy cohort study based in Western Australia. Serial fetal biometric measurements of these participants were collected via ultrasound scans performed at 18, 24, 28, 34, and 38 weeks' gestation. At a 20-year follow-up, the participants underwent a comprehensive ophthalmic examination, including cycloplegic autorefraction and ocular biometry measurements. Using a group-based trajectory modeling approach, we identified groups of participants with similar growth trajectories b

SUBMITTER: Dyer KIC 

PROVIDER: S-EPMC7774062 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature