Structure-Function Analysis in Macular Drusen With Mesopic and Scotopic Microperimetry.

ABSTRACT:

Purpose

To investigate the structure-function relationship in eyes with drusen with mesopic and scotopic microperimetry.

Methods

We analyzed structural and functional data from 43 eyes with drusen. Functional data were acquired with mesopic and scotopic two-color (red and cyan) microperimetry. Normative values were calculated using data from 56 healthy eyes. Structural measurements were green autofluorescence and dense macular optical coherence tomography scans. The latter were used to calculate the retinal pigment epithelium elevation (RPE-E) and the photoreceptor reflectivity ratio (PRR). The pointwise structure-function relationship was measured with linear mixed models having the log-transformed structural parameters as predictors and the sensitivity loss (SL, deviation

SUBMITTER: Montesano G 

PROVIDER: S-EPMC7774115 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature