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Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa.

ABSTRACT: Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.

SUBMITTER: Heinrich F

PROVIDER: S-EPMC7774572 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa.

Heinrich Fabian F Meißner Kira K Langenwalder Felicia F Püschel Klaus K Nörz Dominik D Hoffmann Armin A Lütgehetmann Marc M Aepfelbacher Martin M Bibiza-Freiwald Eric E Pfefferle Susanne S Heinemann Axel A

Emerging infectious diseases 20201216 1

Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem. ...[more]

PMID: 33327991

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