Differentiating between non-functioning pituitary macroadenomas and sellar meningiomas using ADC.

ABSTRACT:

Introduction and aim

It is difficult to distinguish between non-functioning pituitary macroadenomas (NFPMAs) and sellar meningiomas because of their overlapping imaging manifestations on routine MRI, especially in cases of meningiomas growing into the saddle. Here, we aimed to differentiate between these two tumors using apparent diffusion coefficient (ADC) values and MRI characteristics.

Methods

A total of 60 NFPMA and 52 sellar meningioma cases confirmed by the pathological analysis were retrospectively reviewed. All patients were examined via routine MRI and diffusion-weighted imaging (DWI) before undergoing surgery. The clinical characteristics, MRI characteristics, and max ADC (ADCmax), average ADC (ADCmean), and minimum ADC (ADCmin) values were compared between the two

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7774768 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature