An unbiased template of the Drosophila brain and ventral nerve cord.

ABSTRACT: The fruit fly Drosophila melanogaster is an important model organism for neuroscience with a wide array of genetic tools that enable the mapping of individual neurons and neural subtypes. Brain templates are essential for comparative biological studies because they enable analyzing many individuals in a common reference space. Several central brain templates exist for Drosophila, but every one is either biased, uses sub-optimal tissue preparation, is imaged at low resolution, or does not account for artifacts. No publicly available Drosophila ventral nerve cord template currently exists. In this work, we created high-resolution templates of the Drosophila brain and ventral nerve cord using the best-available technologies for imaging, artifact correction, stitching, and template constructio

SUBMITTER: Bogovic JA 

PROVIDER: S-EPMC7774840 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature