Point-of-care characterization and risk-based management of oral lesions in primary dental clinics: A simulation model.

ABSTRACT:

Objectives

Oral potentially malignant disorders (OPMDs) encompass histologically benign, dysplastic, and cancerous lesions that are often indistinguishable by appearance and inconsistently managed. We assessed the potential impact of test-and-treat pathways enabled by a point-of-care test for OPMD characterization.

Materials and methods

We constructed a decision-analytic model to compare life expectancy of test-treat strategies for 60-year-old patients with OPMDs in the primary dental setting, based on a trial for a point-of-care cytopathology tool (POCOCT). Eight strategies of OPMD detection and evaluation were compared, involving deferred evaluation (no further characterization), prompt OPMD characterization using POCOCT measurements, or the commonly recommended usual care

SUBMITTER: Kang SK 

PROVIDER: S-EPMC7774939 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature