The incidence of and risk factors for late presentation of childhood chronic kidney disease: A systematic review and meta-analysis.

ABSTRACT:

Background

When detected early, inexpensive measures can slow chronic kidney disease progression to kidney failure which, for children, confers significant morbidity and impacts growth and development. Our objective was to determine the incidence of late presentation of childhood chronic kidney disease and its associated risk factors.

Methods

We searched MEDLINE, Embase, PubMed, Web of Science, Cochrane Library and CINAHL, grey literature and registry websites for observational data describing children <21 years presenting to nephrology services, with reference to late presentation (or synonyms thereof). Independent second review of eligibility, data extraction, and risk of bias was undertaken. Meta-analysis was used to generate pooled proportions for late presentation by de

SUBMITTER: Plumb L 

PROVIDER: S-EPMC7774987 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature