The use of methylprednisolone in COVID-19 patients: A propensity score matched retrospective cohort study.

ABSTRACT:

Purpose

To evaluate the efficacy and safety of methylprednisolone in treating the coronavirus disease 2019 (COVID-19) patients.

Methods

A retrospective cohort study was conducted, and all COVID-19 patients were recruited who were admitted to the Yichang Third People's Hospital from February 1st to March 31st, 2020. One-to-one propensity score matching (PSM) was used for minimizing confounding effects. The primary outcome was hospital mortality, with the secondary outcomes being the time needed for a positive SARS-CoV-2 nucleic acid test to turn negative and the length of hospital stay.

Results

Totaling 367 patients with COVID-19 hospitalized at the Yichang Third People's Hospital were identified, of whom 276 were mild or stable COVID-19, and 67 were serious or critica

SUBMITTER: You X 

PROVIDER: S-EPMC7775059 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature