Association of Brain Iron Overload With Brain Edema and Brain Atrophy After Intracerebral Hemorrhage.

ABSTRACT: Objective: This study evaluated iron overload after intracerebral hemorrhage (ICH) using ESWAN sequences. Methods: This single-center prospective observational cohort study enrolled supratentorial ICH patients. MRI was obtained with a 3.0-T scanner at day 1, day 14, day 30, and follow-up (300 days or later). R2* mapping was generated based on the ESWAN. R2* value of the ipsilateral side represented iron deposition, and the R2* value of the contralateral side served as control. R2* value was adjusted by volume and used to assess total iron overload. Brain edema was measured on T2 FLAIR-weighted images. Brain atrophy was calculated as the contralateral hemisphere volume minus the injured hemisphere volume. Results: Twnety-seven patients with a spontaneous supratentorial

SUBMITTER: Liu R 

PROVIDER: S-EPMC7775517 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature