Respiration-averaged CT versus standard CT attenuation map for correction of ¹⁸F-sodium fluoride uptake in coronary atherosclerotic lesions on hybrid PET/CT.

ABSTRACT:

Background

To evaluate the impact of respiratory-averaged computed tomography attenuation correction (RACTAC) compared to standard single-phase computed tomography attenuation correction (CTAC) map, on the quantitative measures of coronary atherosclerotic lesions of ¹⁸F-sodium fluoride (¹⁸F-NaF) uptake in hybrid positron emission tomography and computed tomography (PET/CT).

Methods

This study comprised 23 patients who underwent ¹⁸F-NaF coronary PET in a hybrid PET/CT system. All patients had a standard single-phase CTAC obtained during free-breathing and a 4D cine-CT scan. From the cine-CT acquisition, RACTAC maps were obtained by averaging all images acquired over 5 seconds. PET reconstructions using either CTAC or RACTAC were compared. The

SUBMITTER: Tzolos E 

PROVIDER: S-EPMC7775905 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature