Biofilm and cell adhesion strength on dental implant surfaces via the laser spallation technique.

ABSTRACT:

Objective

The aims of this study are to quantify the adhesion strength differential between an oral bacterial biofilm and an osteoblast-like cell monolayer to a dental implant-simulant surface and develop a metric that quantifies the biocompatible effect of implant surfaces on bacterial and cell adhesion.

Methods

High-amplitude short-duration stress waves generated by laser pulse absorption are used to spall bacteria and cells from titanium substrates. By carefully controlling laser fluence and calibration of laser fluence with applied stress, the adhesion difference between Streptococcus mutans biofilms and MG 63 osteoblast-like cell monolayers on smooth and rough titanium substrates is obtained. The ratio of cell adhesion strength to biofilm adhesion strength (i.e., Adhesi

SUBMITTER: Boyd JD 

PROVIDER: S-EPMC7775913 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature