Propedia: a database for protein-peptide identification based on a hybrid clustering algorithm.

ABSTRACT:

Background

Protein-peptide interactions play a fundamental role in a wide variety of biological processes, such as cell signaling, regulatory networks, immune responses, and enzyme inhibition. Peptides are characterized by low toxicity and small interface areas; therefore, they are good targets for therapeutic strategies, rational drug planning and protein inhibition. Approximately 10% of the ethical pharmaceutical market is protein/peptide-based. Furthermore, it is estimated that 40% of protein interactions are mediated by peptides. Despite the fast increase in the volume of biological data, particularly on sequences and structures, there remains a lack of broad and comprehensive protein-peptide databases and tools that allow the retrieval, characterization and understanding of pr

SUBMITTER: Martins PM 

PROVIDER: S-EPMC7776311 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature