Reducing Antibiotic Use in Ambulatory Care Through Influenza Vaccination.

ABSTRACT:

Background

Improving appropriate antibiotic use is crucial for combating antibiotic resistance and unnecessary adverse drug reactions. Acute respiratory illness (ARI) commonly causes outpatient visits and accounts for ~41% of antibiotics used in the United States. We examined the influence of influenza vaccination on reducing antibiotic prescriptions among outpatients with ARI.

Methods

We enrolled outpatients aged ≥6 months with ARI from 50-60 US clinics during 5 winters (2013-2018) and tested for influenza with RT-PCR; results were unavailable for clinical decision making and clinical influenza testing was infrequent. We collected antibiotic prescriptions and diagnosis codes for ARI syndromes. We calculated vaccine effectiveness (VE) by comparing vaccination odds among infl

SUBMITTER: Smith ER 

PROVIDER: S-EPMC7778345 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature