Kawasaki disease and influenza-new lessons from old associations.

ABSTRACT: Kawasaki disease (KD), an enigmatic medium vessel vasculitis, presents as an acute febrile illness predominantly affecting young children. KD appears to be a hyper-inflammatory response elicited by environmental or infectious agents (including respiratory viruses) in genetically predisposed individuals. Numerous reports from the current era of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have described the occurrence of KD/KD-like illness in close temporal proximity to SARS-CoV-2 infection or exposure. Notably, KD has been reported in association with H₁N₁-pdm09 virus that caused the previous pandemic a decade ago. Non-H₁N₁ influenza infections as well as influenza vaccination have also been reported to trigger KD. Herein

SUBMITTER: Banday AZ 

PROVIDER: S-EPMC7778392 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature