RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions.

ABSTRACT: RNA-protein complexes have emerged as central players in numerous key cellular processes with significant relevance in health and disease. To further deepen our knowledge of RNA-binding proteins (RBPs), multiple proteome-wide strategies have been developed to identify RBPs in different species leading to a large number of studies contributing experimentally identified as well as predicted RBP candidate catalogs. However, the rapid evolution of the field led to an accumulation of isolated datasets, hampering the access and comparison of their valuable content. Moreover, tools to link RBPs to cellular pathways and functions were lacking. Here, to facilitate the efficient screening of the RBP resources, we provide RBP2GO (https://RBP2GO.DKFZ.de), a comprehensive database of all currently avai

SUBMITTER: Caudron-Herger M 

PROVIDER: S-EPMC7778890 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature