CSVS, a crowdsourcing database of the Spanish population genetic variability.

ABSTRACT: The knowledge of the genetic variability of the local population is of utmost importance in personalized medicine and has been revealed as a critical factor for the discovery of new disease variants. Here, we present the Collaborative Spanish Variability Server (CSVS), which currently contains more than 2000 genomes and exomes of unrelated Spanish individuals. This database has been generated in a collaborative crowdsourcing effort collecting sequencing data produced by local genomic projects and for other purposes. Sequences have been grouped by ICD10 upper categories. A web interface allows querying the database removing one or more ICD10 categories. In this way, aggregated counts of allele frequencies of the pseudo-control Spanish population can be obtained for diseases belonging to the

SUBMITTER: Pena-Chilet M 

PROVIDER: S-EPMC7778906 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature