Long-term results of definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma.

ABSTRACT:

Purpose

The present study aimed to evaluate the long-term results of definitive chemoradiotherapy (CRT) for unresectable locally advanced esophageal squamous cell carcinoma (LA-ESCC).

Materials and methods

We analyzed eighty patients with unresectable LA-ESCC, who underwent definitive CRT between 2001 and 2014. The 5-year overall survival (OS), cause-specific survival (CSS), and progression-free survival (PFS) rates were calculated, and we investigated the prognostic factors and adverse events.

Results

The median age was 66 years (range, 41-83 years). Histologically, all patients had squamous cell carcinoma. The most common tumor site was the middle thoracic esophagus in 43 (54%) patients. According to the eighth edition of the Union for International Cancer Control T

SUBMITTER: Ochi M 

PROVIDER: S-EPMC7779346 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature