Near Real-Time Surveillance to Assess the Safety of the 9-Valent Human Papillomavirus Vaccine.

ABSTRACT:

Background and objectives

Human papillomavirus is the most common sexually transmitted infection in the United States and causes certain anogenital and oropharyngeal cancers. The 9-valent human papillomavirus vaccine (9vHPV) provides protection against additional types not included in the quadrivalent vaccine. We conducted near real-time vaccine safety surveillance for 24 months after the vaccine became available in the Vaccine Safety Datalink.

Methods

Immunizations and adverse events were extracted weekly from October 2015 to October 2017 from standardized data files for persons 9 to 26 years old at 6 Vaccine Safety Datalink sites. Prespecified adverse events included anaphylaxis, allergic reaction, appendicitis, Guillain-Barré syndrome, chronic inflammatory demyelinating p

SUBMITTER: Donahue JG 

PROVIDER: S-EPMC7780202 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature