Midline lesions of the prostate: role of MRI/TRUS fusion biopsy and implications in Gleason risk stratification.

ABSTRACT:

Purpose

MRI-TRUS fusion biopsy (FBx) has proven efficacy in targeting suspicious areas that are traditionally missed by systematic 12-core biopsy (SBx). Midline prostate lesions are undersampled during SBx, as traditional approaches aim laterally during TRUS biopsy. The aim of our study was to determine the utility of FBx for targeting midline lesions identified on multiparametric MRI (mpMRI).

Methods

A review was performed of a prospectively maintained database of patients undergoing mpMRI followed by FBx and SBx from 2007 to 2015. Midline location was defined as any lesion crossing the midline on axial imaging and involving both prostatic lobes. Index lesion was defined as lesion with highest Gleason score on biopsy. Patient demographic, imaging, and histopathologic data w

SUBMITTER: Muthigi A 

PROVIDER: S-EPMC7780236 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature