Hirschsprung-associated enterocolitis in children treated at US children's hospitals.

ABSTRACT:

Background

The incidence of and risk factors for Hirschsprung's-associated enterocolitis (HAEC) following pull-through have been limited to single institutions studies. We characterized the incidence of, risk factors for, and consequences of post-operative HAEC.

Methods

We identified children with Hirschsprung's Disease (HD) at US Children's Hospitals from 2007 to 2017 with and an associated pull-through operation at less than 1 year of age. HAEC readmissions were identified using ICD9/10 Diagnosis Codes and antibiotic administration. Hierarchical logistic regression models were developed for the risk factors for HAEC after pull-through and effects of recurrent HAEC on HD-related reoperations.

Results

We identified 2030 children with HD, and 138 (7%) who had two or mo

SUBMITTER: Pruitt LCC 

PROVIDER: S-EPMC7780549 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature