Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways.

ABSTRACT: Myelin destruction and oligodendrocyte (OL) death consequent to metabolic stress is a feature of CNS disorders across the age spectrum. Using cells derived from surgically resected tissue, we demonstrate that young (

SUBMITTER: Fernandes MGF 

PROVIDER: S-EPMC7782481 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature