Identifying the Distinct Cognitive Phenotypes in Multiple Sclerosis.

ABSTRACT:

Importance

Cognitive impairment is a common and disabling feature of multiple sclerosis (MS), but a precise characterization of cognitive phenotypes in patients with MS is lacking.

Objectives

To identify cognitive phenotypes in a clinical cohort of patients with MS and to characterize their clinical and magnetic resonance imaging (MRI) features.

Design, setting, and participants

This multicenter cross-sectional study consecutively screened clinically stable patients with MS and healthy control individuals at 8 MS centers in Italy from January 1, 2010, to October 31, 2019. Patients with MS and healthy control individuals who were not using psychoactive drugs and had no history of other neurological or medical disorders, learning disability, severe head trauma, and alco

SUBMITTER: De Meo E 

PROVIDER: S-EPMC7783596 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature