Auditory localization should be considered as a sign of minimally conscious state based on multimodal findings.

ABSTRACT: Auditory localization (i.e. turning the head and/or the eyes towards an auditory stimulus) is often part of the clinical evaluation of patients recovering from coma. The objective of this study is to determine whether auditory localization could be considered as a new sign of minimally conscious state, using a multimodal approach. The presence of auditory localization and the clinical outcome at 2 years of follow-up were evaluated in 186 patients with severe brain injury, including 64 with unresponsive wakefulness syndrome, 28 in minimally conscious state minus, 71 in minimally conscious state plus and 23 who emerged from the minimally conscious state. Brain metabolism, functional connectivity and graph theory measures were investigated by means of ¹⁸F-fluorodeoxyglucose positro

SUBMITTER: Carriere M 

PROVIDER: S-EPMC7784043 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature