Enhanced nutrient uptake is sufficient to drive emergent cross-feeding between bacteria in a synthetic community.

ABSTRACT: Interactive microbial communities are ubiquitous, influencing biogeochemical cycles and host health. One widespread interaction is nutrient exchange, or cross-feeding, wherein metabolites are transferred between microbes. Some cross-fed metabolites, such as vitamins, amino acids, and ammonium (NH₄⁺), are communally valuable and impose a cost on the producer. The mechanisms that enforce cross-feeding of communally valuable metabolites are not fully understood. Previously we engineered a cross-feeding coculture between N₂-fixing Rhodopseudomonas palustris and fermentative Escherichia coli. Engineered R. palustris excretes essential nitrogen as NH₄⁺ to E. coli, while E. coli excretes essential carbon as fermentation products to R. palustr

SUBMITTER: Fritts RK 

PROVIDER: S-EPMC7784955 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature