In-silico protein-ligand docking studies against the estrogen protein of breast cancer using pharmacophore based virtual screening approaches.

ABSTRACT: Breast cancer in woman is the most common cancer and in 2018 there were around 2 million new cases recorded. The maximum rate of breast cancer is reported in Belgium followed by Luxembourg. It is the second most general cancer, Lung cancer being the first. If the cancer tumor is located only in the breast, the survival rate would be 99%. If the tumor has wide to lymph nodes around the survival rate would be 85% and if the tumor had extend to distant parts, the survival rate would come down to 27%. Mammary gland is an important organ in mammals which has potential function to secrete, synthesize and deliver milk to the infants for nourishment, improvement and protection. Generally, cancer is named after the body part in which it originated; thus, breast cancer refers to the erratic developm

SUBMITTER: Sahayarayan JJ 

PROVIDER: S-EPMC7785421 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature