Effect of Lactobacillus brevis CD2 containing lozenges and plaque pH and cariogenic bacteria in diabetic children: a randomised clinical trial.

ABSTRACT:

Objective

The short-term effect (60 days) of Lactobacillus brevis CD2 lozenges vs placebo on variables related to caries and gingivitis in type 1 diabetic children was evaluated.

Material and methods

Eight diabetics (4-14 years old) were assigned to two groups (n = 34 subjects each), probiotic lozenges and placebo. Stimulated saliva for microbiological analysis and plaque pH were assessed at baseline (t₀), 30 days (t₁), 60 days (t₂) and in the follow-up period (90 days from baseline, t₃). Gingival status was assessed at t₀, t₂ and t₃. Two-way ANOVA assessed differences between groups.

Results

In the probiotic group, Streptococcus mutans bacterial density mean scores dropped from 3.11 ± 1.13 a

SUBMITTER: Lai S 

PROVIDER: S-EPMC7785539 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature