Molecular Epidemiology and Risk Factors of Clostridium difficile ST81 Infection in a Teaching Hospital in Eastern China.

ABSTRACT:

Background

The prevalence of Clostridium difficile causes an increased morbidity and mortality of inpatients, especially in Europe and North America, while data on C. difficile infection (CDI) are limited in China.

Methods

From September 2014 to August 2019, 562 C. difficile isolates were collected from patients and screened for toxin genes. Multilocus sequence typing (MLST) and antimicrobial susceptibility tests by E-test and agar dilution method were performed. A case group composed of patients infected with sequence type (ST) 81 C. difficile was compared to the non-ST81 infection group and non CDI diarrhea patients for risk factor and outcome analyses.

Results

The incidence of inpatients with CDI was 7.06 cases per 10,000 patient-days. O

SUBMITTER: Yang Z 

PROVIDER: S-EPMC7785937 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature