Aberrant Metabolic Patterns Networks in Insular Epilepsy.

ABSTRACT: Introduction: Insular epilepsy is clinically challenging. This study aimed to map cerebral metabolic networks in insular epilepsy and investigate their graph-theoretic properties, with the goal of elucidating altered metabolic network architectures that underlie interictal hypometabolism. Aims: Fluorine-18-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG-PET) imaging was performed in 17 individuals with a stereoelectroencephalography (SEEG) confirmed diagnosis of insula epilepsy and 14 age- and sex-matched healthy comparison individuals. Metabolic covariance networks were mapped for each group and graph theoretical analyses of these networks were undertaken. For each pair of regions comprising a whole-brain parcellation, regionally-averaged FDG uptake value

SUBMITTER: Zhao B 

PROVIDER: S-EPMC7786135 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature