In vitro intestinal toxicity of commercially available spray disinfectant products advertised to contain colloidal silver.

ABSTRACT: The use of colloidal silver-containing products as dietary supplements, immune boosters and surface disinfectants has increased in recent years which has elevated the potential for human exposure to silver nanoparticles and ions. Product mislabeling and long-term use of these products may put consumers at risk for adverse health outcomes including argyria. This study assessed several physical and chemical characteristics of five commercial products as well as their cytotoxicity using a rat intestinal epithelial cell (IEC-6) model. Concentrations of silver were determined for both the soluble and particulate fractions of the products. Primary particle size distribution and elemental composition were determined by transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscop

SUBMITTER: Rogers KR 

PROVIDER: S-EPMC7786200 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature