Detection of Recurrent Prostate Cancer With ¹⁸F-Fluciclovine PET/MRI.

ABSTRACT:

Objective

Simultaneous PET/MRI combines soft-tissue contrast of MRI with high molecular sensitivity of PET in one session. The aim of this prospective study was to evaluate detection rates of recurrent prostate cancer by ¹⁸F-fluciclovine PET/MRI.

Methods

Patients with biochemical recurrence (BCR) or persistently detectable prostate specific antigen (PSA), were examined with simultaneous ¹⁸F-fluciclovine PET/MRI. Multiparametric MRI (mpMRI) and PET/MRI were scored on a 3-point scale (1-negative, 2-equivocal, 3-recurrence/metastasis) and detection rates (number of patients with suspicious findings divided by total number of patients) were reported. Detection rates were further stratified based on PSA level, PSA doubling time (PSAdt), primary treatment and

SUBMITTER: Selnæs KM 

PROVIDER: S-EPMC7786298 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature