The interaction of shockwaves with a vapour bubble in boiling histotripsy: The shock scattering effect.

ABSTRACT: Boiling histotripsy is a High Intensity Focused Ultrasound (HIFU) technique which uses a number of short pulses with high acoustic pressures at the HIFU focus to induce mechanical tissue fractionation. In boiling histotripsy, two different types of acoustic cavitation contribute towards mechanical tissue destruction: a boiling vapour bubble and cavitation clouds. An understanding of the mechanisms underpinning these phenomena and their dynamics is therefore paramount to predicting and controlling the overall size of a lesion produced for a given boiling histotripsy exposure condition. A number of studies have shown the effects of shockwave heating in generating a boiling bubble at the HIFU focus and have studied its dynamics under boiling histotripsy insonation. However, not much is known

SUBMITTER: Pahk KJ 

PROVIDER: S-EPMC7786583 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature