Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis.

ABSTRACT:

Objective

To determine the effects of coenzyme Q10 (CoQ10) for reduction in the severity, frequency of migraine attacks and duration of headache in adult patients with migraine.

Design

Systematic review and meta-analysis.

Data sources

Cochrane Central Register of Controlled Trials, CENTRAL, MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Psychological Information Database (PsycINFO) from inception till December 2019.

Study selection

All randomised control trials comparing CoQ10 with placebo or used as an adjunct treatment included in this meta-analysis. Cross-over designs and controlled clinical trials were excluded.

Data synthesis

Heterogeneity at face value by comparing populations, settings, interventions and out

SUBMITTER: Sazali S 

PROVIDER: S-EPMC7786797 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature