Cerebral haemodynamics with head position changes post-ischaemic stroke: A systematic review and meta-analysis.

ABSTRACT: The effects of upright postures on the cerebral circulation early post-ischaemic stroke are not fully understood. We conducted a systematic review and meta-analysis to investigate the effects of head positioning on cerebral haemodynamics assessed by imaging methods post-ischaemic stroke. Of the 21 studies included (n = 529), 15 used transcranial Doppler. Others used near-infrared, diffuse correlation spectroscopy and nuclear medicine modalities. Most tested head positions between 0° and 45°. Seventeen studies reported changes in CBF parameters (increase at lying-flat or decrease at more upright) in the ischaemic hemisphere with position change. However, great variability was found and risk of bias was high in many studies. Pooled data of two studies ≤24 h (n = 28) showed a me

SUBMITTER: Carvalho LB 

PROVIDER: S-EPMC7786838 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature