TEMPy2: a Python library with improved 3D electron microscopy density-fitting and validation workflows.

ABSTRACT: Structural determination of molecular complexes by cryo-EM requires large, often complex processing of the image data that are initially obtained. Here, TEMPy2, an update of the TEMPy package to process, optimize and assess cryo-EM maps and the structures fitted to them, is described. New optimization routines, comprehensive automated checks and workflows to perform these tasks are described.

SUBMITTER: Cragnolini T 

PROVIDER: S-EPMC7787107 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature