Long-Term Efficacy and Safety of Anti-Obesity Treatment: Where Do We Stand?

ABSTRACT:

Purpose of review

As a chronic and relapsing disease, obesity impairs metabolism and causes cardiovascular diseases. Although behavioral modification is important for the treatment of obesity, it is difficult to achieve an ideal weight or sustain the process of long-term weight loss. Therefore, the obesity control guidelines strongly recommend lifestyle interventions along with medical treatment for patients who are overweight. There is sufficient evidence supporting that pharmacotherapy in combination with behavior-based interventions can result in significant weight loss and improved cardiometabolism.

Recent findings

Recent meta-analyses of new anti-obesity drugs and their weight-loss efficacy have shown that the overall placebo-subtracted weight reduction (%) for at least

SUBMITTER: Tak YJ 

PROVIDER: S-EPMC7787121 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature